| Y's | SMS |
| Y's 3: Wanderers From Y's | SNES |
| Y's 3: Wanderers From Y's | GEN |
| Yars' Revenge | 2600 |
| Yars' Revenge | GBC |
| Yo! Noid | NES |
| Yoshi | NES |
| Yoshi | GB |
| Yoshi's Cookie | NES |
| Yoshi's Cookie | GB |
| Yoshi's Cookie | SNES |
| Yoshi's Safari | SNES |
| Young Indiana Jones Chronicles | NES |
| Young Indiana Jones in Instruments of Chaos | GEN |
| Young Merlin | SNES |
| Yu Yu Hakushu Tournament Tactics | GBA |
| Yu-Gi-Oh! 7 Trials to Glory | GBA |
| Yu-Gi-Oh! Dark Duel Stories | GBC |
| Yu-Gi-Oh! Destiny Board Travaler | GBA |
| Yu-Gi-Oh! Double Pack 2 | GBA |
| Yu-Gi-Oh! Dungeon Dice Monsters | GBA |
| Yu-Gi-Oh! Reshef of Destruction | GBA |
| Yu-Gi-Oh! The Eternal Duelist Soul | GBA |
| Yu-Gi-Oh! The Sacred Cards | GBA |
| Yu-Gi-Oh! World Championship Tournament 2004 | GBA |
| Yu-Gi-Oh! World Wide Edition Stairway to the Destined Duel | GBA |
| Yu-Yu-Yakusho: Spirit Detective | GBA |
| Zanac | NES |
| Zany Golf | GEN |
| Zapper One Wicked Cricket! | GBA |
| Zatch Bell! Electric Arena | GBA |
| Zaxxon | COL |
| Zaxxon 3-D | SMS |
| Zebco Fishing! | GBC |
| Zen Intergalactic Ninja | NES |
| Zenji | COL |
| Zero the Kamikaze Squirrel | SNES |
| Zero the Kamikaze Squirrel | GEN |
| Zero Tolerance | GEN |
| Zillion | SMS |
| Zillion 2 Triformation | SMS |
| Zoey 101 | GBA |
| Zombie Nation | NES |
| Zombies Ate My Neighbors | GEN |
| Zombies Ate My Neighbors | SNES |
| Zool | SNES |
| Zool | GEN |
| Zool | SGG |
| Zoom! | GEN |
| Zoop | GEN |
| Zoop | SNES |
| Zoop | SGG |